BiosanBio

About Us

Biosan Biotechnology

Biosan Biotechnology started its R&D studies in Tubitak Marmara Teknokent "R&D and Innovation Center" in 2015 and attaches great importance to its work in the field of medical devices. As Biosan Biotechnology, we continue our product development studies as well as the production of medical devices offered with Hyaluronic Acid-based Pre-filled Injection, whose R&D studies were completed in 2021.

WHAT IS OSTEOARTHRITIS (OA)?

Osteoarthritis (OA) is known as the most common chronic disease of the cartilage. As the cartilage breaks down due to wear-and-tear and/or mechanical stress, it causes swelling, pain and inflammation, leading to extracellular matrix (ECM) loss¹ .
Knee osteoarthritis (KOA) is a progressive joint disease that often involves intra- and per articular structures² and is considered pathology characterized by articular cartilage lesions, synovitis, subchondral sclerosis, and osteophytes³.
Knee osteoarthritis (OA) is most often a slowly progressive joint disorder characterized by cartilage degeneration and inflammation⁴. Knee OA commonly results in knee pain and decreases patients’ mobility (e.g. walking and stair climbing)⁵.
The pain of osteoarthritis is usually related to activity. For osteoarthritis of the knee (Fig. 1), activities such as climbing stairs, getting out of a chair, and walking long distances bring on pain. Morning stiffness usually lasts less than 30 minutes.⁶ Patients often note that their knees “give way,” a so-called instability symptom.

OSTEOARTRİT (OA) SYMPTOMES

The joint pain of OA typically is described as being exacerbated by activity and relieved by rest. More advanced OA can cause pain at rest and during the night, leading to loss of sleep that further exacerbates pain.